Cyclic Neutropenia is a rare genetic disorder characterized by recurrent episodes of abnormally low levels of neutrophils, a type of white blood cell that plays a crucial role in the immune system. The condition is inherited in an autosomal dominant manner, meaning that an affected individual has a 50% chance of passing the gene mutation to their offspring.
The exact prevalence of Cyclic Neutropenia is not well-established, as it is a rare disorder and often goes undiagnosed or misdiagnosed. However, it is estimated to affect approximately 1 in every 1 million individuals worldwide. The condition typically manifests in infancy or early childhood, with symptoms including recurrent infections, oral ulcers, fever, and fatigue.
Diagnosis of Cyclic Neutropenia is based on a complete blood count (CBC) that reveals cyclic fluctuations in neutrophil counts. Treatment options aim to manage symptoms and prevent infections, and may include the use of antibiotics, granulocyte colony-stimulating factor (G-CSF) to boost neutrophil production, and regular monitoring of blood counts.
It is important for individuals with suspected Cyclic Neutropenia to consult with a healthcare professional for proper evaluation, diagnosis, and management. Ongoing research and advancements in genetic testing techniques may contribute to a better understanding of the prevalence and management of this rare disorder.
by Diseasemaps