Empty Sella Syndrome is a condition characterized by the enlargement or partial collapse of the sella turcica, a bony structure in the skull that houses the pituitary gland. This syndrome occurs when the sella turcica becomes filled with cerebrospinal fluid, causing it to appear empty on imaging tests.
The prevalence of Empty Sella Syndrome is difficult to determine precisely due to its often asymptomatic nature. However, studies suggest that it is relatively common, with an estimated prevalence ranging from 5% to 25% in the general population. The condition is more frequently observed in women, particularly those who are overweight or have a history of hormonal imbalances.
Empty Sella Syndrome can be congenital or acquired, with the latter often resulting from conditions such as pituitary tumors, trauma, or radiation therapy. While many individuals with this syndrome may remain asymptomatic, some may experience symptoms related to hormonal imbalances or compression of surrounding structures.
Diagnosis of Empty Sella Syndrome typically involves imaging tests, such as magnetic resonance imaging (MRI), to visualize the sella turcica. Treatment is usually focused on managing any underlying hormonal imbalances or associated symptoms, rather than directly addressing the empty sella itself.