Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a rare genetic disorder characterized by fragile bones that break easily. The prevalence of OI varies depending on the specific type and population studied.
According to medical literature, OI affects approximately 1 in 15,000 to 20,000 individuals worldwide. However, it is important to note that this estimate may not capture the true prevalence as milder cases can go undiagnosed or misdiagnosed.
There are different types of OI, ranging from mild to severe, with varying frequencies. The most severe forms are less common, affecting around 1 in 100,000 individuals. On the other hand, the milder forms, which may present with fewer fractures and less severe symptoms, are more prevalent.
Due to the rarity of OI, it is considered an orphan disease, meaning it affects a small percentage of the population. However, the impact on individuals and families living with OI can be significant, requiring specialized medical care, support, and adaptive measures to manage the condition.