Spondyloepiphyseal Dysplasia Tarda (SEDT) is a rare genetic disorder that affects bone and cartilage development. It is characterized by short stature, abnormal curvature of the spine, and joint deformities. SEDT is caused by mutations in the COL2A1 gene, which is responsible for producing a protein called type II collagen that is essential for the normal development of bones and cartilage.
SEDT is an inherited condition, meaning it is passed down from parents to their children. It follows an autosomal dominant pattern of inheritance, which means that a person with SEDT has a 50% chance of passing the condition on to each of their children.
It is important to note that SEDT is not contagious. It cannot be transmitted from person to person through any means, including physical contact or exposure to bodily fluids. SEDT is solely a genetic disorder that is present from birth.
While SEDT is not contagious, it is a lifelong condition that requires ongoing medical management. Treatment options may include physical therapy, orthopedic interventions, and surgical procedures to address the skeletal abnormalities and improve quality of life.