Is Superior Mesenteric Artery Syndrome hereditary?

Here you can see if Superior Mesenteric Artery Syndrome can be hereditary. Do you have any genetic components? Does any member of your family have Superior Mesenteric Artery Syndrome or may be more predisposed to developing the condition?


Is Superior Mesenteric Artery Syndrome hereditary?


Superior Mesenteric Artery Syndrome (SMAS) is a rare condition that affects the digestive system. It occurs when the duodenum, the first part of the small intestine, becomes compressed between two major blood vessels in the abdomen - the abdominal aorta and the superior mesenteric artery. This compression can lead to various symptoms, including abdominal pain, nausea, vomiting, and weight loss.


When it comes to the hereditary nature of SMAS, there is limited scientific evidence available. The exact cause of SMAS is not fully understood, and it is believed to be multifactorial, meaning that several factors contribute to its development. While some cases of SMAS have been reported in families, suggesting a potential genetic component, the majority of cases are considered sporadic, occurring without a clear family history.


Research into the genetic basis of SMAS is ongoing, and several studies have investigated potential genetic factors that may contribute to the development of this condition. However, no specific genes or inheritance patterns have been definitively linked to SMAS at this time.


It is important to note that the absence of a clear genetic link does not rule out the possibility of genetic factors playing a role in SMAS. Genetic predisposition, combined with other environmental or anatomical factors, may contribute to the development of the condition. Additionally, the rarity of SMAS makes it challenging to conduct large-scale genetic studies to determine its hereditary nature.


While the hereditary aspect of SMAS remains uncertain, it is crucial to focus on the diagnosis and management of the condition. If you or someone you know is experiencing symptoms suggestive of SMAS, it is essential to consult with a healthcare professional for a thorough evaluation and appropriate diagnostic tests.


In conclusion, the hereditary nature of Superior Mesenteric Artery Syndrome is not well-established. While some cases have been reported in families, the majority of cases are considered sporadic. Ongoing research aims to uncover potential genetic factors contributing to SMAS, but no specific genes or inheritance patterns have been definitively linked to the condition. If you suspect SMAS, it is important to seek medical attention for proper diagnosis and management.


by Diseasemaps

Can be but is very rare!

5/28/18 by Alexis 2500

Having children and grandchildren myself I have often wondered and worried about this particular question. However I do not know the answers. And I don't believe there's enough research out there to prove it one way or another. That's the problem with a rare disease. The research that goes into it is very minimal.

6/13/18 by Shawn 1024

YES!! My grandfather had it. My mother had it. She allowed the duodeal bypass and passed at age 58. I have it and I am 46. And now my 16 year old daughter has been diagnosed with it. YES, it is hereditary.

7/31/18 by Stacee 1150

I think Superior Mesenteric Artery Syndrome can be hereditary but, isn't always hereditary. There are some who get it from surgery and other show symptoms at a young age.

3/14/20 by Macy Mae 2550

In some families it does run in the family others it doesnt

1/28/21 by Babypay1 2650

Smas is not hereditary but have had cases of identical twins

5/18/21 by Sarah Steffen 1100

I believe there is some hereditary component for some people- otherwise how would you explain families with multiple family members being diagnosed with SMAS.

8/27/22 by Staci 300

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