Adult-onset Still's Disease (AOSD) is a rare inflammatory disorder that primarily affects adults. It is characterized by persistent high fevers, joint pain, rash, and systemic inflammation. AOSD is considered an autoinflammatory disease, meaning it results from an abnormal response of the immune system.
The exact cause of AOSD is unknown, but it is believed to involve a combination of genetic and environmental factors. The symptoms of AOSD can vary widely among individuals, making it challenging to diagnose. However, certain key features such as spiking fevers, joint involvement, and distinctive rash can aid in diagnosis.
Treatment for AOSD aims to control symptoms and prevent complications. Nonsteroidal anti-inflammatory drugs (NSAIDs) may be prescribed to manage pain and inflammation. In more severe cases, corticosteroids or immunosuppressive medications may be necessary. Additionally, lifestyle modifications and physical therapy can help improve joint function and overall well-being.
While AOSD can be a chronic condition, many individuals experience periods of remission where symptoms subside. However, it is important to regularly monitor the disease and manage symptoms to prevent long-term complications.