Alport Syndrome is a rare genetic disorder that primarily affects the kidneys, ears, and eyes. It is caused by mutations in certain genes responsible for producing collagen, a crucial component of connective tissues in the body.
The prevalence of Alport Syndrome varies across different populations. In general, it is estimated to affect approximately 1 in 5,000 to 10,000 individuals worldwide. However, the prevalence can be higher in certain regions or specific populations due to genetic factors.
Alport Syndrome can be inherited in different patterns, including X-linked, autosomal recessive, and autosomal dominant. The X-linked form is the most common, accounting for about 80% of cases. This means that males are more frequently affected, while females can be carriers or have milder symptoms.
Early diagnosis and management of Alport Syndrome are crucial to prevent or delay the progression of kidney disease and associated complications. Genetic testing and regular monitoring of kidney function, hearing, and vision are essential for individuals with suspected or confirmed Alport Syndrome.