What are the best treatments for Ankylosing Spondylitis?

See the best treatments for Ankylosing Spondylitis here


Treatments for Ankylosing Spondylitis


Ankylosing Spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and reduced mobility. While there is no cure for AS, there are several treatment options available to manage symptoms, slow down disease progression, and improve quality of life for individuals with this condition.



1. Medications


Nonsteroidal anti-inflammatory drugs (NSAIDs): These are often the first line of treatment for AS. NSAIDs help reduce pain, inflammation, and stiffness. Over-the-counter options like ibuprofen and naproxen can be effective, but prescription-strength NSAIDs may be necessary for more severe symptoms.


Disease-modifying antirheumatic drugs (DMARDs): DMARDs such as sulfasalazine and methotrexate can help slow down the progression of AS and reduce inflammation. They are typically used when NSAIDs alone are not sufficient.


Biologic agents: Biologics, such as tumor necrosis factor (TNF) inhibitors (e.g., etanercept, adalimumab), are a newer class of medications that target specific molecules involved in the inflammatory process. They can effectively reduce symptoms and slow down disease progression in many individuals with AS.



2. Physical Therapy


Exercise: Regular physical activity and specific exercises can help improve flexibility, posture, and overall function. A physical therapist can design an exercise program tailored to an individual's needs and abilities. Low-impact activities like swimming and cycling are often recommended.


Posture training: Learning proper posture and body mechanics can help reduce pain and prevent deformities caused by AS. Physical therapists can provide guidance on maintaining good posture during daily activities.


Stretching and strengthening exercises: Stretching exercises can help improve flexibility and reduce stiffness, while strengthening exercises can enhance muscle support for the spine and joints.



3. Pain Management


Heat and cold therapy: Applying heat or cold to affected areas can help alleviate pain and reduce inflammation. Heat therapy, such as warm showers or heating pads, can relax muscles and improve blood circulation. Cold therapy, such as ice packs, can numb the area and reduce swelling.


Transcutaneous electrical nerve stimulation (TENS): TENS involves the use of a small device that delivers low-voltage electrical currents to the skin, which can help relieve pain by blocking pain signals.


Acupuncture: Some individuals find acupuncture helpful in managing pain and improving overall well-being. It involves the insertion of thin needles into specific points on the body to stimulate energy flow.



4. Surgery


Joint replacement: In severe cases where AS has caused significant joint damage and disability, joint replacement surgery may be considered. This typically involves replacing the damaged joint with an artificial joint, such as a hip or knee replacement.



5. Lifestyle Modifications


Good posture: Maintaining proper posture can help reduce pain and prevent spinal deformities. Using ergonomic chairs and pillows, as well as avoiding prolonged sitting or standing, can be beneficial.


Quit smoking: Smoking has been linked to more severe symptoms and faster disease progression in AS. Quitting smoking can improve overall health and potentially reduce the impact of AS.


Stress management: Stress can worsen symptoms of AS. Engaging in stress-reducing activities such as meditation, yoga, or hobbies can help improve overall well-being.



It is important for individuals with AS to work closely with their healthcare team to develop a personalized treatment plan. The effectiveness of treatments may vary from person to person, and a combination of approaches is often necessary to manage symptoms and maintain a good quality of life.


by Diseasemaps

For myself, the best treatment is to stay active, get my remicade infusions on time and don't overdo anything.

3/4/17 by Denise 450

Since there is no cure for AS, some medications help to ease the symptoms (like biologics and Nonsteroidal anti-inflammatory drugs or NSAIDs, see http://www.mayoclinic.org/diseases-conditions/ankylosing-spondylitis/diagnosis-treatment/treatment/txc-20261171), but in a lot of cases other treatments help great deal, too: physical therapy, food supplements (natural anti-inflammatory pills like curcumin or boswellia; omega 3; vitamin D3; etc.), anti-inflammatory diets (low to no starch, gluten, sugar; more protein & fermented food). A lot of movement and meditation goes a long way, too. Mind you, these natural, less invasive treatments are not a cure for the disease, they ease the symptoms and are only efficient in the long run!

3/4/17 by kat1 1050

To begin with Physical therapy and occupational therapy is great. Water therapy was the best of them all. It helps with mobility and strengthening. Accupunctire and massage works well for some too and light exercise and yoga. Movement is the key to AS . when all other treatments fails there are medications such as biologics, Methotrexate, Plaquinel, Sulfanazine, pain meds and some antidepressants that help to relieve pain as well as slow the progression of the disease. There is no cure but more treatment options are becoming available.

3/4/17 by Heather 1120

Humira, NSAIDs and exercise

3/5/17 by Richard Deery 600

Biologic medications. Ice. Steroids, methotrexate.

5/17/17 by Shannon 1050

Exercise, NSAIDs and then biologics

5/17/17 by Keli 1050

Naproxen and humira. Avoid tramadol for pin relief

5/17/17 by Simon 300

Biologic medication

5/18/17 by Karlie 1150

Medication vitamins movement

5/18/17 by kelly cannell 500

A combination of diet changes, exercise and medications like non steroid anti inflammatory or biologics depending on how the disease has progressed

5/19/17 by Kylie Frost 2120

I am kind of one who does not like many rx drugs, refused a biologic, went on plaquinil and low dose naltrexone at my request, I am doing pretty good. I used to use Norco, and no longer need it!

5/19/17 by Tamra 1750

Activity while you can, anti-inflammatories, tnf blockers or other immune suppressants.

7/24/17 by 1000

NSAIDS. TNFs, physical therapy, hydrotherapy. rest

8/31/17 by BigStu111 12832

Biologic medicine, remicade, enbrel, humira. And methotrexate.

9/6/17 by Daniel Wilson 2010

Best treatment in general is staying active and walk or train your body at least once a week.

9/7/17 by Luciano Scariano 2600

Bio meds Pain meds Proper diet Exercise Staying active

9/7/17 by Carol 600

Biologics to slow axial portion of the disease and other agents for peripheral portion; movement is better than being static, with light exercise; warmth bit low humidity

9/10/17 by Sal 4050

Natural Herbs, Diet, Exercise,Swimming

9/21/17 by Rana Navid Anwaar Khan 3945

Farmaci di fondo Farmaci biotecnologici

10/1/17 by Silvia 2500

Well I am no one to really answer this and the studies are evolving daily thankfully. But it is known that some treatment help but the efficiency may vary on people. List of some treatment known to help AS condition: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) TNF Inhibtors Corticosteroids (temporary relief on zone injected) Methotrexate (at a much smaller dose than for cancer) And not to be forgotten that all guidelines recommend that beside treatment exercice is a key! (range of motion, flexibility, cardio, etc.)

2/16/18 by Laeti 3570

Injectable TNF Inhibitors have worked best for me and most others, sometimes coupled with methotrexate, a chemo theraputic drug, corticosteroids, nsaids, or minocycline. Also, staying active. Water activities, walking and yoga are best. Physically therapy and massage therapy also help.

5/31/18 by Colleen 2550
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Biological medicinal products type humira and Remicade in my opinion are the most effective treatments.

8/10/17 by Andressa. Translated
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Diet without starch, stretching, exercise, and Humira.

8/14/17 by Luz. Translated
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Treatment with medicine biological

8/15/17 by Adriana. Translated

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