Autoimmune Hemolytic Anemia (AIHA) is a rare condition characterized by the immune system mistakenly attacking and destroying red blood cells. This leads to a decrease in the number of healthy red blood cells, causing anemia. Cold Agglutinin Disease (CAD) is a specific type of AIHA where the immune system produces antibodies that bind to red blood cells at low temperatures, causing them to clump together (agglutinate) and be destroyed.
The symptoms of AIHA/CAD can vary but often include fatigue, weakness, pale skin, shortness of breath, and jaundice. In CAD, symptoms may worsen in cold environments or after exposure to cold temperatures. Diagnosis involves blood tests to detect the presence of autoantibodies and assess red blood cell destruction.
Treatment for AIHA/CAD aims to suppress the immune system and manage symptoms. This may involve corticosteroids, immunosuppressive drugs, blood transfusions, and avoiding cold temperatures. In severe cases, splenectomy (surgical removal of the spleen) may be considered.
Early diagnosis and appropriate treatment are crucial in managing AIHA/CAD and improving quality of life for affected individuals. Regular follow-up with healthcare professionals is important to monitor blood counts and adjust treatment as needed.
by Diseasemaps