What are the best treatments for Cluster Headaches?

See the best treatments for Cluster Headaches here


Treatments for Cluster Headaches


Cluster headaches are excruciatingly painful headaches that occur in cyclical patterns or clusters. They are often described as the most severe type of headache and can significantly impact a person's quality of life. While there is no cure for cluster headaches, several treatments can help alleviate the pain, reduce the frequency of attacks, and improve overall well-being.



1. Acute Treatments


Acute treatments aim to relieve the intense pain experienced during a cluster headache attack. These treatments are typically fast-acting and can be administered at the onset of an attack. Some effective acute treatments include:




  • High-flow oxygen therapy: Inhaling pure oxygen through a mask at a flow rate of 12-15 liters per minute can provide rapid relief from cluster headache pain. Oxygen therapy is safe, non-invasive, and has minimal side effects.

  • Triptans: Triptans are a class of medications that can help constrict blood vessels and reduce inflammation in the brain. They are available in various forms, including injections, nasal sprays, and tablets. Sumatriptan and zolmitriptan are commonly prescribed triptans for cluster headaches.

  • Local anesthetics: Lidocaine or other local anesthetics can be administered intranasally to numb the nerves in the nasal passages and provide temporary relief from cluster headache pain.



2. Preventive Treatments


Preventive treatments aim to reduce the frequency and intensity of cluster headache attacks. These treatments are typically taken on a daily basis, even during headache-free periods. Some effective preventive treatments include:




  • Verapamil: Verapamil is a calcium channel blocker that is often considered the first-line preventive medication for cluster headaches. It helps relax blood vessels and prevent the onset of attacks. Regular monitoring of blood pressure and heart rate is necessary while taking verapamil.

  • Steroids: Short courses of oral steroids, such as prednisone, can be prescribed to break a cluster headache cycle and provide temporary relief. However, long-term use of steroids is generally not recommended due to potential side effects.

  • Lithium: Lithium, commonly used for bipolar disorder, has shown effectiveness in preventing cluster headaches. Regular blood tests are required to monitor lithium levels and ensure safety.

  • Calcitonin gene-related peptide (CGRP) monoclonal antibodies: CGRP monoclonal antibodies, such as erenumab and galcanezumab, are a newer class of preventive medications specifically designed for migraines. They have also shown promise in reducing the frequency of cluster headache attacks.



3. Neuromodulation Therapies


Neuromodulation therapies involve the use of devices to stimulate specific nerves or brain regions to prevent or relieve cluster headache attacks. These therapies are often considered when medications alone are insufficient. Some commonly used neuromodulation therapies include:




  • Occipital nerve stimulation (ONS): ONS involves the implantation of a small device that delivers electrical impulses to the occipital nerves at the back of the head. This stimulation can help prevent cluster headache attacks or reduce their intensity.

  • Transcranial magnetic stimulation (TMS): TMS uses magnetic fields to stimulate specific areas of the brain associated with cluster headaches. It is a non-invasive procedure that can be performed in a healthcare provider's office.

  • Deep brain stimulation (DBS): DBS involves the surgical implantation of electrodes in specific brain regions to modulate abnormal activity. While DBS is still being studied for cluster headaches, it has shown promise in some cases.



4. Lifestyle Modifications


Alongside medical treatments, certain lifestyle modifications can help manage cluster headaches and reduce their impact. These include:




  • Avoiding triggers: Identifying and avoiding triggers that can precipitate cluster headache attacks, such as alcohol, certain foods, strong smells, and changes in sleep patterns.

  • Establishing a routine: Maintaining a regular sleep schedule, eating balanced meals, and managing stress can help reduce the frequency of cluster headaches.

  • Keeping a headache diary: Keeping a record of headache patterns, triggers, and treatment effectiveness can provide valuable insights for healthcare providers and aid in developing personalized treatment plans.



It is important for individuals with cluster headaches to work closely with their healthcare providers to determine the most suitable treatment approach. Treatment plans may vary depending on the individual's specific symptoms, medical history, and response to different therapies. With the right combination of treatments, cluster headache sufferers can find relief and regain control over their lives.


by Diseasemaps

I have found that Neurostimulation has been the best course of treatment for me. It has given me my life back. Is it perfect no, I still have attacks but I will take the 90-95 percent improvement. Sumatriptan injections are the best abortive I have found for myself.

2/21/17 by Lucas 1152

Oxygen 15 minutes Imitrex 6 mg PRF

3/3/17 by Yoda 4292

For the most rapid result I find Maxalt to be the best. Naramig and Zomig are good if you address the shadows early enough and the cluster doesn't come on too quickly. Lirica at night may also help. In the meantime Advil, black coffee and energy drinks help as a preventative.

3/4/17 by Donna 1005

I find the sumitriptan injections work really well

4/26/17 by Scott Wright 401

Currently i find the best treatment for clusters are varapamil, oxygen and sumtriptan injections.

4/26/17 by Mike Parkinson 300

Sumatriptan injections are a god send. Unfortunately I'm only allowed two per day which is of little comfort when you can suffer upto 10 allowed tacks per day. High flow O2 helps but it does take a while to work and it's not always effective. I take ceramic 20th per day during cycle also

4/27/17 by Matthew Bcfc 1000

Oxygen. Sumatriptan. Corticoids. Verapamil.

5/21/17 by Pepe922 2000

Oxygen. Veraprimal. Doing nasal spray. Solmitriptan injections.

6/3/17 by Maria 2001

Oxygen at 15 litters

6/4/17 by Tim 2150

Sumatriptan is very effective. Unfortunately after years of use it has ravsged my heart. Ice on my face the second i k now the pain is coming.

6/9/17 by Melissa 400

Have not found a good one if something helps the effect wear's off in 6 to 8 week's then right back where started

6/11/17 by Jeff D 2000

oxygen at 15 litres per minute through a non rebreather mask for 15 minutes. Naramig can work well, but must be taken on a empty stomach at precisely the right time. Just as the pin prick feeling starts behind the eye. Still can't stop waking up with them so today i am going to find some mushrooms to bust the cluster. It's an extreme measure to take but I have to do something about it and it worked years ago

7/21/17 by Jamie 200

Oxygene with a high preasure Mask. If the attack dont breaks. Sumatriptan injekt. Or you use Ascotop Nasal. To stop a cicle you can use Cortison ( Prednisolon or Urbanisol) while you sweap in Verapamil. A second Helper vcan also be lithium or Toparimat.

9/13/17 by patric 200

It interely depends on the specific case/person. Sumatriptans and steroids, mostly.

9/14/17 by João Pedro Graça 500

Oxygen at least 15L per minute, Sumatriptan, and Vetapmil and Melatonin as prophylactic measures.

9/14/17 by Tracie 515

Imitrex has been effective, opioids have had no affect.

9/23/17 by stan 1000

High flow oxygen works for some, nerve blocks work temporarily, and sumatriptan helps dull the pain. A variety of pharmaceuticals can help prevent attacks but they don't work for everyone and have awful side effects for many.

10/26/17 by Lee-Alison 2000

First-line acute treatments include high-flow oxygen and sumatriptan injections. Primary preventives include verapamil, topiramate, divalproex sodium, and lithium.

1/29/18 by Tammy 1150

oxygen Imitrex injections Lidocaine injections to the back of the neck

2/1/18 by Danny 3050

Sumatriptan Nasal spray is the faster and most effective for me. Oxygen helps although I dont usually have it at hand, only when I go to a hospital.

8/29/18 by Nandarq 500

Triptanes, Oxygen

10/20/18 by Michael Trapp 1600

sumatriptan injection to kill the pain verapamil on a daily treatment during the cycle (under heart doctor supervision) Oxygen

11/7/18 by Oliver 3000

Oxygen 100% Immigran injectables Ketamine beta blockkers or neuro stimulator & al lot more to discover i hope And it doesn't go away but just can lighten or shorten the attack.

11/7/18 by MC 2500

Cortisone and oxygen

5/16/19 by vasilis 2500

Oxygen is the most effective treatment for me. I have tried many different remedies and nothing works as well or as long-acting as high-flow oxygen, 12-15 lpm through a non-rebreather mask for at least 10 minutes. Then you can administer your back-up medications to get rid of the shadows, which for me is Advil and coffee, a 1/2 teaspoon of salt mixed in a cup of water to help with the dizziness, and then I'm feeling normal again.

5/20/19 by Kendra 4550

High-flow Oxygen, Sumatriptan, Aimovig

8/22/19 by Judy 1600

High flow Oxygen using a non-rebreather mask is by far the best abortive. Second best abortive is Sumatriptan. Either injection or nasal inhaler.

9/8/19 by By-Tor 100

I have had good results with cannabinoids combined with meditation and exercise.

4/13/20 by Larry 5050

sumatriptan in injection form High flow oxygen through a trauma mask Greater occipital nerve blocks Preventative treatments such as verapamil / gammacore

7/27/20 by Stėph 3000

High flow Oxygen therapy A decent Neuro / headache specialist Greater occipital nerve block Preventative treatments such as gammacore, calcium channel blockers - verapamil Sumatriptan injections

7/27/20 by Stephanie 4650

Prednisone tapers during cluster xyxle help with the severity. The best abortive I have found is sumatriptan 6mg injections.

8/3/21 by Hali 900

25 mg sumitryptan (imitrex) nasal spray reduces a 2-3 hour headache to 15-20 minutes. Works 90% of the time for me.

5/20/22 by randalnowack@aol.com 2500
Translated from spanish Improve translation

I am with Verapamil as a preventative and in crises oxygen that if I work

5/9/17 by Nélida. Translated

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