What is the prevalence of CRPS Complex Regional Pain Syndrome?

How many people does CRPS Complex Regional Pain Syndrome affect? Does it have the same prevalence in men and women? And in the different countries?


Complex Regional Pain Syndrome (CRPS) is a relatively rare and debilitating chronic pain condition. While it is challenging to determine the exact prevalence of CRPS due to underdiagnosis and misdiagnosis, studies suggest that it affects approximately 1.2% to 26.2% of individuals with peripheral nerve injuries or fractures.


CRPS can occur at any age, but it is more commonly observed in individuals between 20 and 35 years old. It is also more prevalent in women than in men, with a female-to-male ratio ranging from 2:1 to 4:1.


The condition can arise after various triggers, such as trauma, surgery, or even minor injuries. It is characterized by severe and disproportionate pain, swelling, changes in skin temperature, and abnormal skin color or texture in the affected area.


Early diagnosis and appropriate treatment are crucial for managing CRPS and improving outcomes. If you suspect you may have CRPS, it is essential to consult with a healthcare professional for an accurate diagnosis and personalized treatment plan.


by Diseasemaps

Seventy-four cases of CRPS I were identified, resulting in an incidence rate of 5.46 per 100,000 person years at risk, and a period prevalence of 20.57 per 100,000. Female:male ratio was 4:1, with a median age of 46 years at onset. Upper limb was affected twice as commonly as lower limb.

9/6/17 by norma.mark@icloud.com 5060

Not realy aware though have learnt it can effect male and female, young and old.

9/13/17 by Andy 3550

A study done by Mayo Clinic in 2003 reviewed records from 1989-1999 and found an incidence rate of 5.46 per 100,000 person. A Dutch study placed the incidence rate at 26.2 per 100,000. The lack of prevalence of registered patients may underestimate the true prevalence of CRPS by 50%. Female:male ratio was 4:1, with a median age of 46 years at onset. Upper limb was affected twice as commonly as lower limb. All cases reported an antecedent event and fracture was the most common trigger (46%). The National Institutes of Health have estimated that 2-5% of people who have a peripheral nerve injury (such as a sprain or fracture, bullet wound, cut or needle stick) will develop CRPS.

9/15/17 by DrLisa 3750

CRPS can affect anyone and is quite common of those people who come under the chronic pain spectrum

9/19/17 by Alex 2550

Very low. Less than 200k per year get it. 90% of people have type 1 and 10% have type 2. Type 2 is the worse diagnosis of the 2.

11/11/17 by Robbie 2000

It is rare approximation less than 200,000 people are diagnosed yearly. It affects men, women children and there are no boundaries. It is not as likely in young kids, seems to be diagnosed in adults over the ages of 20 and up

11/11/17 by Aj 2000

I've read that there are about 200,000 cases diagnosed each year, making it fairly rare. It seems to affect women more than men, adults more than children, with women above age 30 being the most frequently diagnosed.

11/11/17 by Colleen85201 1700

This is a rare disease starting at age 14.

11/12/17 by Shanna 5000

It seems to be uncommon. I don't know if it affects men more than women or children more than adults.

11/12/17 by ladyff1481 2050

CRPS doesn't discriminate -- it's a disease for all. Women are most at risk, but I think that's only because we are more likely to admit pain. Sadly children also get this beast. Its more common in adults but children tend to respond best to treatment.

11/13/17 by Thea 3150

I have looked at many statistics and found different opinions. What I saw was women are three times more likely than men. Teenager's have lower incidence than adults. And there are around 200,000 a year in the U.S. who suffer. It is a rare condition.

11/1/18 by Judy 3000

26.2 out of every 100,000 people are affected by CRPS. Three times more women get it than men. Children can get is but it is a very low percentage.

1/5/19 by Cynthia 4000

Everything I read says more women than me have this. Rare Fewer than 200,000 US cases per year Don't you feel special

1/16/21 by Patricia 3050

Not sure Not as rare as it was due to publicity. Burning Nights CRPS and other orhanisations can answer that. I have personally only met one other person with this fondition. In the county where we live in the UK which is geographically vast there are not many. May be 10 or posdibly more than than that but I am the only one in the town of over 30 000 people with CRPS

11/3/22 by Heather 5020

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