Factor V Leiden is a genetic disorder that affects blood clotting. It is also known by several other names, including:
- Activated protein C resistance: This term refers to the resistance of the protein C, which is involved in regulating blood clotting, in individuals with Factor V Leiden.
- APCR: APCR stands for Activated Protein C Resistance, which is another name for Factor V Leiden.
- FVL: FVL is an abbreviation for Factor V Leiden, commonly used in medical literature and discussions.
- Factor V R506Q: This term refers to the specific genetic mutation that causes Factor V Leiden. The mutation involves a substitution of amino acid arginine (R) with glutamine (Q) at position 506 of the Factor V protein.
- Resistance to activated protein C: This name highlights the underlying mechanism of Factor V Leiden, where individuals have reduced sensitivity to the anticoagulant effects of activated protein C.
These synonyms are often used interchangeably to describe the same condition, Factor V Leiden. It is important to note that Factor V Leiden is the most common inherited risk factor for abnormal blood clotting, particularly in individuals of European descent. The condition increases the risk of developing deep vein thrombosis (DVT), pulmonary embolism (PE), and other clotting disorders.