Glycogen Storage Disease (GSD) is a group of rare genetic disorders characterized by the body's inability to properly store and release glycogen, a form of glucose used for energy. GSD affects both males and females of all ethnic backgrounds.
The prevalence of GSD varies depending on the specific type. GSD type I, also known as von Gierke disease, is the most common form and affects approximately 1 in every 100,000 to 200,000 individuals worldwide. This type is more prevalent in certain populations, such as Ashkenazi Jews, where the incidence can be as high as 1 in 20,000.
Other types of GSD, such as type II (Pompe disease) and type III (Cori disease), have a lower prevalence. Pompe disease affects about 1 in every 40,000 to 60,000 individuals, while Cori disease is estimated to affect 1 in every 100,000 to 130,000 individuals.
It is important to note that the prevalence of GSD may vary across different regions and populations. Due to the rarity of these disorders, accurate prevalence data can be challenging to obtain.
Glycogen Storage Disease (GSD) is a group of rare genetic disorders characterized by the body's inability to properly store and release glycogen. The prevalence of GSD varies depending on the specific type, with GSD type I being the most common form. Other types, such as Pompe disease and Cori disease, have a lower prevalence. It is important to note that accurate prevalence data can be challenging to obtain due to the rarity of these disorders.