Prader-Willi Syndrome (PWS) is a rare genetic disorder that affects approximately 1 in every 10,000 to 30,000 individuals worldwide. It is characterized by a variety of physical, cognitive, and behavioral symptoms. PWS occurs equally in males and females and across all ethnicities.
The prevalence of Prader-Willi Syndrome varies depending on the population being studied. In newborns, the prevalence is estimated to be around 1 in 20,000 to 1 in 25,000 births. However, the prevalence increases significantly in individuals with developmental disabilities or intellectual disabilities, where it is estimated to be as high as 1 in 3,000 to 1 in 15,000 individuals.
PWS is caused by the absence or non-functioning of certain genes on chromosome 15 inherited from the father. The syndrome is typically characterized by hypotonia (low muscle tone), hyperphagia (excessive appetite), developmental delays, short stature, and characteristic facial features. Individuals with PWS often face challenges related to obesity, intellectual disabilities, behavioral issues, and hormonal imbalances.
While Prader-Willi Syndrome is considered a rare disorder, it is important to raise awareness about its prevalence and provide support to individuals and families affected by this condition.