What are the best treatments for Relapsing Polychondritis?

See the best treatments for Relapsing Polychondritis here


Relapsing Polychondritis (RP) is a rare autoimmune disease that primarily affects the cartilage in the body, causing inflammation and damage. While there is no cure for RP, there are several treatment options available to manage the symptoms and slow down the progression of the disease.



1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs such as ibuprofen or naproxen can help reduce pain and inflammation associated with RP. These medications are available over-the-counter and can provide temporary relief.



2. Corticosteroids: Corticosteroids are powerful anti-inflammatory drugs that can effectively control inflammation in RP. They can be administered orally, topically, or through injections, depending on the severity of symptoms. However, long-term use of corticosteroids may lead to side effects, so they are typically prescribed at the lowest effective dose for the shortest duration.



3. Disease-Modifying Antirheumatic Drugs (DMARDs): DMARDs such as methotrexate or azathioprine are often used in RP to suppress the immune system and reduce inflammation. These medications can help prevent further damage to the cartilage and other organs affected by the disease.



4. Biologic Therapies: Biologic drugs, such as tumor necrosis factor (TNF) inhibitors or interleukin-1 (IL-1) inhibitors, are a newer class of medications used in RP treatment. These drugs specifically target the immune system and can be effective in managing symptoms and preventing relapses.



5. Immunosuppressants: In severe cases of RP, stronger immunosuppressant medications like cyclophosphamide or mycophenolate mofetil may be prescribed. These medications work by suppressing the immune system to reduce inflammation and prevent further damage.



6. Symptom Management: In addition to medication, various therapies can help manage specific symptoms of RP. For example, if RP affects the respiratory system, bronchodilators or oxygen therapy may be recommended. Physical therapy can also be beneficial in maintaining joint mobility and reducing pain.



7. Regular Monitoring: Regular check-ups with healthcare professionals are crucial for monitoring the progression of RP and adjusting treatment plans accordingly. This allows for early detection of any complications and ensures that the most appropriate treatment is provided.



It is important to note that the effectiveness of treatments may vary from person to person, and a combination of different approaches may be necessary. Therefore, it is essential for individuals with RP to work closely with their healthcare team to develop a personalized treatment plan that addresses their specific needs.


by Diseasemaps

Prednisone, methotrexate and Plaquenil

4/26/17 by Freya 1000

Steroids in the short term. Then a disease modtfying drug such as methotrexate Relapsing Polychondritis does not have a cure but it can often be well controlled with medication. Disease-modifying anti rheumatic drugs like Methotrexate and Prednisolone (Corticosteroids) are often given to suppress the immune system. For milder cases of the condition, non-steroidal, anti-inflammatory drugs and painkillers may be prescribed. Where the airways are involved, surgery may be required to repair the windpipe (trachea) or stenting to keep the airway open.

4/27/17 by Lisa Matthews (Lissy) 4800

Out of my own experience biologics have helped a lot but still sometimes cortizone is a must. Many other meds can be used in combination.

4/27/17 by Laoura 2050

High dose prednisone during a flare. Methotrexate, cyclophosphamide

8/9/17 by Louise C 1450

In the beginning I believe it's a good idea to try ibuprofen & other NSAIDS then if that does not help decrease symptoms, most likely moving on to steroids as usually destruction is occurring throughout the body & needs to get under control.

8/14/17 by Susan 2000

So far for me nothing has worked like Prednisone.

9/1/17 by Diane 2050

Oral steroids, clean diet, immunosuppressants. LDN

6/11/19 by Brooketaylornp@gmail.com 1000

Prednisone and methotrexate

6/12/19 by Tmrcarlson 3550

Methotrexate, imuran, cellcept, humira, remicade, Rituximab, cytoxan are some of the most common. Also anti inflammatory medication like Celebrex, colchicine, mobic etc Prednisone is commonly used for relapsing polychondritis and for most assists in controlling flares in high doses. Some remain on a maintenance dose in combination with other drugs as above and at times increase dosages to control flares.

6/12/19 by Kaz 3000

Immunosuppressants Steroids Biologics

12/30/19 by Leanne 2500

Steroid medications, DMARDs, anti inflammatory medications, biologics, pain relief

12/30/19 by Carrie 3050

dapsone and colchicine quiet symptoms. Currently taking infusions of zolair.

3/20/22 by shlawver 2500

Actemra helps me so much. Its better than steroids outside of a few severe flairs.FIGHTING MEDICARE FOR INJECTOR PEN SO INFUSION WILL NOT BE NEEDED.

4/16/22 by Dee 100
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Up to now has not how to evaluate the treatments, they are all the cortisone, and we all know what effects this treatment brings us...

10/1/17 by Ana Luiza Bottura. Translated
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Immunomodulatory treatments

10/2/17 by cmomo. Translated
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I realize that the most used are corticosteroids, biological and Metrotexato.

10/2/17 by Glaucia. Translated
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Immunosuppressive and corticodes.

10/2/17 by Carolina. Translated
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For the time methotrexate, but my I keep getting outbreaks very often. Short-term corticosteroids

10/2/17 by Sandra. Translated

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