What is Relapsing Polychondritis

Relapsing Polychondritis description. Find out what Relapsing Polychondritis is and know more about it.


Relapsing Polychondritis is a rare autoimmune disorder that primarily affects the cartilage in the body. It is characterized by recurrent episodes of inflammation in various cartilaginous structures, such as the ears, nose, joints, and respiratory tract.


The exact cause of Relapsing Polychondritis is unknown, but it is believed to involve an abnormal immune response where the body's immune system mistakenly attacks its own cartilage. This can lead to symptoms such as pain, swelling, redness, and deformity in the affected areas.


Diagnosis of Relapsing Polychondritis can be challenging as its symptoms can mimic other conditions. Medical history, physical examination, and imaging tests are typically used to evaluate the extent of cartilage inflammation. Treatment aims to control inflammation and manage symptoms, often involving the use of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and immunosuppressive medications.


Relapsing Polychondritis is a chronic condition that tends to have unpredictable flare-ups and remissions. It can affect individuals of any age, but it is more commonly diagnosed in middle-aged adults. Early detection and appropriate management are crucial in minimizing cartilage damage and improving quality of life for those living with this condition.


by Diseasemaps

Relapsing Polychondritis (RP) is a rare, progressive condition characterised by recurrent episodes of inflammation of cartilaginous structures. These include the ears, nose, upper respiratory tract, chest wall and joints. Other organs and tissues may also become involved such as the eye, inner ear, heart, blood vessels and kidneys. ​ The exact cause of Relapsing Polychondritis (RP) is not known. However, it is believed to be an autoimmune disorder where the body's immune system starts attacking its own healthy cells believing them to be foreign. ​ RP has an episodic pattern with periods of intense inflammation and periods of remission and dependant on the severity of the inflammatory process, often requiring the use of immune suppressant medications. ​ RP can be life threatening, debilitating and difficult to diagnose and prognosis is variable, depending on organ involvement and treatment complications. Where the disease is mild or responds quickly to treatment, there is a good prognosis. ​ Relapsing Polychondritis is also known by other names such as Meyenburg Altherr Uehlinger syndrome, chronic atrophic polychondritis and Von Meyenburg syndrome. ​

3/20/18 by Lisa Matthews (Lissy) 4800

A disease that destroys the cartilage in your body

6/12/19 by Tmrcarlson 3550

Relapsing polychondritis is a multi-systemic condition characterized by repeated episodes of inflammation and deterioration of cartilage. The often painful disease can cause joint deformity and be life-threatening if the respiratory tract, heart valves, or blood vessels are affected.

6/13/19 by Kaz 3000

Relapsing polychondritis is an extremely rare autoimmune disease that attacks cartilage

12/30/19 by Leanne 2500

Relapsing polychondritis is a rare disease that presents with inflammation of cartilage in several parts of the body, usually affecting the ears, nose, throat and lungs. It occurs most often in people in their 50s or 60s and is more common in people with white/Caucasian ancestry.

12/30/19 by Carrie 3050

The immune system is triggered erratically to respond to normal tissue as if it were the enemy. Mast cells bully the normal cells and tissue.

3/20/22 by shlawver 2500

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