Hereditary Angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of swelling in various body parts, including the face, limbs, gastrointestinal tract, and airways. It is caused by a deficiency or dysfunction of a protein called C1 esterase inhibitor (C1-INH), which leads to uncontrolled activation of certain immune pathways.
The prevalence of HAE varies across different populations. In the United States, it is estimated to affect approximately 1 in every 50,000 individuals. However, this prevalence may be higher due to underdiagnosis and misdiagnosis. HAE can affect both males and females, with symptoms typically appearing during childhood or adolescence.
It is important to note that HAE is an underdiagnosed condition, and many individuals may go undiagnosed or misdiagnosed for years. The symptoms can be debilitating and potentially life-threatening if not properly managed. Prompt diagnosis and appropriate treatment are crucial in improving the quality of life for individuals with HAE.
Disclaimer: The information provided here is for educational purposes only and should not be considered as medical advice. If you suspect you or someone you know may have Hereditary Angioedema, please consult a healthcare professional for proper evaluation and diagnosis.