Cleidocranial Dysplasia (CCD) is a rare genetic disorder that affects the development of bones and teeth. It is caused by mutations in the RUNX2 gene, which plays a crucial role in skeletal development. CCD is not contagious and cannot be transmitted from one person to another.
Individuals with CCD may exhibit various symptoms, including delayed closure of the fontanelles (soft spots on the skull), abnormal collarbones, dental abnormalities, and delayed eruption of permanent teeth. The severity of symptoms can vary widely among affected individuals.
CCD is typically inherited in an autosomal dominant pattern, which means that an affected individual has a 50% chance of passing the condition on to each of their children. However, in some cases, CCD can also occur sporadically, without a family history of the disorder.
Diagnosis of CCD is usually based on clinical evaluation, medical history, and imaging studies such as X-rays. Treatment for CCD is primarily focused on managing the symptoms and may involve dental interventions, orthodontic treatment, and surgical procedures to correct skeletal abnormalities.
It is important to note that while CCD itself is not contagious, individuals with CCD may face certain challenges in their daily lives. Supportive care, early intervention, and regular follow-up with healthcare professionals can help individuals with CCD lead fulfilling lives and manage any associated complications.