Familial Adenomatous Polyposis (FAP) is a relatively rare genetic disorder characterized by the development of numerous polyps in the colon and rectum. These polyps, if left untreated, have a high likelihood of progressing into colorectal cancer. FAP is inherited in an autosomal dominant manner, meaning that an affected individual has a 50% chance of passing the condition on to each of their children.
The prevalence of FAP varies among different populations. In general, it is estimated to affect approximately 1 in 8,000 to 1 in 10,000 individuals worldwide. However, the prevalence may be higher in certain regions or communities with a higher incidence of the specific genetic mutation responsible for FAP.
Early diagnosis and management of FAP are crucial to prevent the development of cancer. Regular screening and surveillance, often involving colonoscopies, are recommended for individuals with a family history of FAP or those who exhibit symptoms associated with the condition.
FAP is a relatively rare genetic disorder affecting approximately 1 in 8,000 to 1 in 10,000 individuals worldwide. Early detection and appropriate medical interventions can significantly reduce the risk of colorectal cancer in affected individuals.