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How is Granuloma Inguinale / Donovanosis diagnosed?

See how Granuloma Inguinale / Donovanosis is diagnosed. Which specialists are essential to meet, what tests are needed and other useful information for the diagnosis of Granuloma Inguinale / Donovanosis

Granuloma Inguinale / Donovanosis diagnosis

Granuloma inguinale, also known as Donovanosis, is a rare sexually transmitted infection caused by the bacterium Klebsiella granulomatis. It primarily affects the genital and perineal regions, causing the development of painless ulcers or nodules. Early diagnosis and treatment are crucial to prevent complications and further transmission.



Diagnosing Granuloma Inguinale



The diagnosis of granuloma inguinale involves a combination of clinical evaluation, laboratory tests, and microscopic examination of tissue samples. The following methods are commonly used:




  1. Physical examination: A healthcare provider will examine the affected area, looking for characteristic signs such as raised, beefy-red ulcers or nodules with a granular appearance. The ulcers may bleed easily upon contact.

  2. Microscopic examination: A sample of tissue or fluid from the ulcer is collected and examined under a microscope. This helps identify the presence of Klebsiella granulomatis bacteria, which appear as rod-shaped organisms within infected cells.

  3. PCR testing: Polymerase chain reaction (PCR) tests can be performed on the collected samples to detect the genetic material of the bacteria. PCR is highly sensitive and specific, allowing for accurate diagnosis.

  4. Tissue culture: In some cases, a tissue sample may be cultured in a laboratory to grow and identify the bacteria. However, this method is less commonly used due to its longer turnaround time.



Additional Considerations



It is important to note that granuloma inguinale can be mistaken for other sexually transmitted infections or skin conditions, such as syphilis, genital herpes, or chancroid. Therefore, a comprehensive evaluation is necessary to rule out other potential causes.



If you suspect you may have granuloma inguinale or have been exposed to it, it is crucial to seek medical attention promptly. Early diagnosis and treatment with appropriate antibiotics, such as doxycycline or azithromycin, can help resolve the infection and prevent complications.


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