I also have Alpha 1. I am 60 years old and was diagnosed maybe 6 years ago. I have an infusion of Aralast every week. I am unsure what to expect as time goes on? I am not much of an exceriser. I am still working and am on my feet all day, sometimes walking 4 -5 miles a day. But that's all I do! I try to eat healthy but I am not very good at that either. My mother died of COPD (she was a smoker) and my dad died of liver disease. Both my lungs and liver are affected. Please let me know if you have any thoughts on this. thanks, Jene