What is the prevalence of Caroli Disease?
How many people does Caroli Disease affect? Does it have the same prevalence in men and women? And in the different countries?
The prevalence of Caroli Disease, a rare congenital disorder affecting the bile ducts, is quite low. It is estimated to occur in approximately 1 in 1,000,000 individuals worldwide. This condition is characterized by the dilation of intrahepatic bile ducts, leading to various complications. Although rare, Caroli Disease can have significant impacts on liver function and overall health. Early diagnosis and appropriate management are crucial for individuals affected by this condition.
Caroli Disease is a rare congenital disorder characterized by the presence of cystic dilatation in the intrahepatic bile ducts. It is considered a form of autosomal recessive polycystic kidney disease (ARPKD) and can affect both the liver and kidneys. The exact prevalence of Caroli Disease is not well-established due to its rarity and the lack of comprehensive population studies.
However, it is estimated that the prevalence of Caroli Disease ranges from 1 in 100,000 to 1 in 1,000,000 individuals worldwide. The condition is more commonly observed in certain populations, such as those with a higher rate of consanguineous marriages. Additionally, Caroli Disease can present at any age, from infancy to adulthood.
Caroli Disease can lead to various complications, including recurrent cholangitis, liver abscesses, biliary stones, and liver fibrosis. In some cases, it may progress to liver failure or require liver transplantation. Early diagnosis and appropriate management are crucial in improving outcomes for individuals with Caroli Disease.
