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Which are the symptoms of Degos Disease?

See the worst symptoms of affected by Degos Disease here

Degos Disease symptoms

Symptoms of Degos Disease


Degos Disease, also known as Malignant Atrophic Papulosis, is a rare and progressive disorder that affects the blood vessels. It primarily affects the skin, but can also involve other organs such as the gastrointestinal tract, central nervous system, and eyes. The exact cause of Degos Disease is unknown, and it predominantly affects adults between the ages of 20 and 50.



Skin Lesions: The most common and characteristic symptom of Degos Disease is the development of skin lesions. These lesions typically start as small, red or purple papules that gradually evolve into raised, firm, and porcelain-white plaques. The lesions have a central depression and a surrounding erythematous rim, giving them a "cayenne pepper" appearance. These skin lesions can occur anywhere on the body but are most commonly found on the trunk, face, and limbs.



Gastrointestinal Involvement: In some cases, Degos Disease can affect the gastrointestinal tract. This can lead to various symptoms such as abdominal pain, nausea, vomiting, diarrhea, and gastrointestinal bleeding. In severe cases, it can cause bowel perforation or obstruction, which requires immediate medical attention.



Central Nervous System Involvement: Degos Disease can also involve the central nervous system, leading to neurological symptoms. These can include headaches, seizures, cognitive impairment, memory loss, difficulty speaking, and changes in behavior. In rare cases, it can cause strokes or transient ischemic attacks (mini-strokes).



Ocular Manifestations: Some individuals with Degos Disease may experience ocular manifestations. These can include inflammation of the eye (uveitis), retinal artery occlusion, or retinal detachment. Ocular involvement can lead to vision loss or blindness if not promptly treated.



Systemic Complications: In advanced stages of Degos Disease, the condition can progress to involve multiple organs, leading to systemic complications. These complications can vary widely and may include problems with the heart, lungs, kidneys, liver, or pancreas. Systemic involvement can significantly impact overall health and may require intensive medical management.



Other Symptoms: Some individuals with Degos Disease may experience general symptoms such as fatigue, weight loss, fever, and muscle or joint pain. These symptoms are non-specific and can be seen in various other conditions, making the diagnosis of Degos Disease challenging.



It is important to note that the symptoms and severity of Degos Disease can vary widely among individuals. Some individuals may have mild skin involvement, while others may experience more severe systemic complications. Early diagnosis and appropriate management are crucial in order to prevent or minimize organ damage and improve overall prognosis.


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Translated from french Improve translation
Still called papulose atrophicans disease, Degos is a disorder of the blood vessels, which takes its name from the one who has identified : Robert Degos. It is characterized by the blockage of blood vessels ; a situation that slows or stops the flow of blood through veins or arteries with. (cf:http://santedoc.com/maladies/dermatoses/maladie-de-degos.html).
The disease Degos is serious as it leads to the dysfunction of several organs, some of which are vital ; causing death in two to three years on average. But in some cases it remains limited to skin lesions on different parts of the body and seems harmless. The symptoms of the disease Degos can vary greatly from one person to another. Cutaneous lesions are the characteristic feature, include white spots that tend to develop on the trunk, arms and legs. For some people it is their only symptom. For others, the disease Degos know of complications and affects multiple organs such as the eyes, kidneys, heart and liver.

The complication of the gastro-intestinal is the result of a lack of blood supply to the intestinal lining and can lead to perforation of the intestine. The usual symptoms are sudden onset of abdominal pain or gastrointestinal bleeding (vomiting of blood). The involvement of the nervous system can lead to strokes, headaches, epilepsy, or neurological symptoms are non-specific such as memory loss or altered sensation.
Source:http://santedoc.com/maladies/dermatoses/maladie-de-degos.html

Posted Sep 3, 2017 by Leila 830

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