Eosinophilic Fasciitis is a rare autoimmune disorder that affects the connective tissues in the body, particularly the fascia. The condition is characterized by inflammation and thickening of the fascia, which is the fibrous tissue that surrounds muscles, blood vessels, and nerves. Eosinophilic Fasciitis primarily affects the arms and legs, causing pain, stiffness, and swelling.
One of the key features of Eosinophilic Fasciitis is the presence of eosinophils, a type of white blood cell, in the affected tissues. These eosinophils contribute to the inflammation and fibrosis seen in the condition. The exact cause of Eosinophilic Fasciitis is unknown, but it is believed to involve an abnormal immune response.
Diagnosis of Eosinophilic Fasciitis involves a combination of clinical evaluation, blood tests, imaging studies, and sometimes a biopsy of the affected tissue. Treatment typically involves the use of immunosuppressive medications to reduce inflammation and control symptoms. Physical therapy may also be recommended to improve mobility and reduce stiffness.
While Eosinophilic Fasciitis is a chronic condition, with proper management, many individuals can experience relief from symptoms and maintain a good quality of life.