What is Food Protein-Induced Enterocolitis Syndrome

Food Protein-Induced Enterocolitis Syndrome (FPIES) is a rare, non-IgE mediated gastrointestinal food allergy that primarily affects infants and young children. It is characterized by delayed onset symptoms, typically occurring a few hours after consuming certain trigger foods.

FPIES symptoms often include repetitive vomiting, diarrhea, and dehydration. In severe cases, it can lead to lethargy, low blood pressure, and even shock. The most common triggers for FPIES are cow's milk and soy, but it can also be triggered by other foods like grains, poultry, and fish.

Diagnosing FPIES can be challenging as symptoms can be mistaken for other conditions. A detailed medical history, elimination diets, and oral food challenges are often used to diagnose FPIES. It is crucial to consult with a healthcare professional for an accurate diagnosis.

Managing FPIES involves strict avoidance of trigger foods and close monitoring of the child's diet. In some cases, infants may require specialized hypoallergenic formulas. As children grow, they may outgrow FPIES, but it is essential to regularly reassess their tolerance to trigger foods under medical supervision.

While FPIES can be distressing for both the child and their caregivers, with proper management and medical guidance, affected individuals can lead healthy lives.