Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) is a genetic disorder that affects the red blood cells' ability to function properly. It is estimated to affect around 400 million people worldwide, making it one of the most common enzyme deficiencies. The prevalence of G6PD deficiency varies among different populations, with higher rates found in certain regions such as Africa, the Mediterranean, and Southeast Asia. The condition is more common in males than females due to its X-linked inheritance pattern. G6PD deficiency can lead to hemolytic anemia, triggered by certain medications, infections, or exposure to certain foods or chemicals.
Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) is a genetic disorder that affects the red blood cells. It is one of the most common enzyme deficiencies worldwide, particularly prevalent in certain populations. G6PD deficiency is inherited in an X-linked recessive manner, meaning that it primarily affects males.
The prevalence of G6PD deficiency varies across different regions and ethnic groups. It is estimated that around 400 million people worldwide have G6PD deficiency, with the highest prevalence found in areas where malaria is or has been endemic. In these regions, the prevalence can be as high as 20-30% of the population.
Specific populations with a high prevalence of G6PD deficiency include individuals of African, Mediterranean, Middle Eastern, and Southeast Asian descent. In some cases, the prevalence can be as high as 10-15% within these populations.
It is important to note that G6PD deficiency can have varying degrees of severity, with some individuals experiencing mild symptoms while others may have more severe reactions to certain triggers, such as certain medications or infections.