Granuloma Inguinale / Donovanosis synonyms
What other names are the Granuloma Inguinale / Donovanosis known by? Synonyms and other terms with which Granuloma Inguinale / Donovanosis is known.
Granuloma Inguinale, also known as Donovanosis, is a rare and chronic bacterial infection that primarily affects the genital and perineal regions. It is caused by the bacterium Klebsiella granulomatis. This sexually transmitted infection (STI) is characterized by the development of painless, progressive ulcers on the genitals or in the groin area.
The symptoms of Granuloma Inguinale usually appear within 1 to 12 weeks after exposure to the bacteria. Initially, small, raised, beefy-red nodules or papules form, which eventually break down to form ulcers. These ulcers are typically painless, have a beefy-red appearance, and may bleed easily upon contact. Without proper treatment, the ulcers can grow larger and deeper, leading to extensive tissue destruction.
Granuloma Inguinale is primarily transmitted through sexual contact, including vaginal, anal, and oral sex. It is more common in tropical and subtropical regions, as well as in areas with poor sanitation and limited access to healthcare. Individuals with weakened immune systems, such as those with HIV/AIDS, are at a higher risk of developing severe and atypical presentations of the infection.
Diagnosis of Granuloma Inguinale is typically made through clinical examination and laboratory tests. A healthcare provider may collect a sample from the ulcer and examine it under a microscope to identify the characteristic Donovan bodies, which are intracellular bacteria found in the infected tissue.
Treatment for Granuloma Inguinale involves a prolonged course of antibiotics, usually with medications such as doxycycline, azithromycin, or ciprofloxacin. It is important to complete the full course of treatment to ensure eradication of the bacteria and prevent relapse. In some cases, surgical intervention may be required to manage complications or extensive tissue damage.
Prevention of Granuloma Inguinale involves practicing safe sex, including the consistent use of condoms, and limiting sexual partners. Regular STI screenings are also important, especially for individuals engaging in high-risk sexual behaviors or living in endemic areas.
