Hemolytic-uremic Syndrome synonyms

Hemolytic-uremic syndrome (HUS) is a rare but serious condition that primarily affects the kidneys and blood. It is often characterized by the triad of symptoms including hemolytic anemia (destruction of red blood cells), thrombocytopenia (low platelet count), and acute kidney injury.

There are several synonyms used to refer to Hemolytic-uremic syndrome, which include:

• Typical HUS: This term is used to describe the most common form of HUS, which is usually caused by infection with certain strains of E. coli bacteria, particularly E. coli O157:H7. Typical HUS is often associated with gastrointestinal symptoms, such as diarrhea, before the onset of the syndrome.


• Atypical HUS: Atypical HUS is a less common form of the syndrome that is not associated with an infection. It is often caused by genetic mutations that affect the regulation of the complement system, a part of the immune system involved in inflammation and cell destruction. Atypical HUS can occur at any age and may have a chronic or recurrent course.


• Post-diarrheal HUS: This term is used when HUS develops following an episode of diarrhea, typically caused by infection with certain strains of E. coli. It is more commonly seen in children and is often associated with a prodromal diarrheal illness.


• Stec-HUS: This synonym is used to highlight the association of HUS with Shiga toxin-producing E. coli (STEC) infections. STEC-HUS is primarily caused by ingestion of contaminated food or water, and it can lead to severe complications.

Hemolytic-uremic syndrome can be a life-threatening condition, particularly in severe cases. It requires prompt medical attention and treatment to manage the complications and prevent long-term kidney damage. Early recognition and intervention are crucial for improving outcomes.