Henoch-Schönlein purpura is a relatively common vasculitis that primarily affects children between the ages of 2 and 11. It is characterized by the deposition of immune complexes in small blood vessels, leading to inflammation and subsequent purpura (purple-colored spots) on the skin. The prevalence of Henoch-Schönlein purpura varies geographically, ranging from 10 to 20 cases per 100,000 children. It is more common in certain populations, such as Asians and Caucasians, and has a slight male predominance. Although it can occur at any age, it is most frequently diagnosed in childhood.
Henoch-Schönlein purpura (HSP) is a relatively common form of vasculitis, primarily affecting children between the ages of 2 and 11 years. Although it can occur at any age, it is most prevalent in this age group. HSP is characterized by inflammation of the small blood vessels, resulting in a distinctive rash known as purpura, which appears as small, raised, reddish-purple spots on the skin.
The exact prevalence of HSP varies across different populations and geographical regions. However, it is estimated that HSP affects approximately 10 to 20 per 100,000 children annually. This prevalence translates to a considerable number of cases worldwide, given the global population of children. HSP is more commonly observed in boys than girls, with a male-to-female ratio of around 1.5:1.
While HSP is generally considered a self-limiting condition, meaning it resolves on its own without treatment, it can lead to various complications in some cases. These complications may include joint pain, gastrointestinal symptoms, kidney involvement, and rarely, more severe systemic manifestations. Prompt medical evaluation and appropriate management are crucial to minimize the risk of complications and ensure a favorable outcome for individuals with HSP.