11

Is Léri-weill Dyschondrosteosis hereditary?

Here you can see if Léri-weill Dyschondrosteosis can be hereditary. Do you have any genetic components? Does any member of your family have Léri-weill Dyschondrosteosis or may be more predisposed to developing the condition?

Is Léri-weill Dyschondrosteosis hereditary?

Léri-Weill Dyschondrosteosis is a genetic disorder that affects bone growth. It is hereditary and follows an autosomal dominant pattern of inheritance. This means that if one parent carries the gene mutation, there is a 50% chance of passing it on to their children. However, it is important to consult with a healthcare professional or genetic counselor for a comprehensive evaluation and understanding of the specific genetic factors involved.



Léri-Weill Dyschondrosteosis (LWD) is a rare genetic disorder that affects bone growth and development. It is characterized by short stature, short forearms and lower legs, and a characteristic deformity of the wrist known as Madelung deformity.


The inheritance pattern of Léri-Weill Dyschondrosteosis is autosomal dominant, which means that an affected individual has a 50% chance of passing the condition on to each of their children. This pattern of inheritance indicates that a single copy of the mutated gene is sufficient to cause the disorder.


The specific gene associated with Léri-Weill Dyschondrosteosis is the SHOX gene, located on the X and Y chromosomes. Mutations in this gene disrupt the normal growth and development of bones, leading to the characteristic features of LWD.


It is important to note that Léri-Weill Dyschondrosteosis can also occur sporadically, meaning that it can arise in individuals with no family history of the condition. In these cases, the mutation in the SHOX gene occurs spontaneously during the formation of reproductive cells or early embryonic development.


Genetic testing can be performed to confirm a diagnosis of Léri-Weill Dyschondrosteosis and to identify the specific mutation in the SHOX gene. This information can be valuable for genetic counseling, as it allows individuals and families to understand the likelihood of passing the condition on to future generations.


Diseasemaps
3 answers
Yes it is hereditary

Posted Oct 13, 2017 by Andrea 3910
It is indeed hereditary and anyone with LWS has a 50/50 chance of passing on to their children. My mom and maternal grandma most definitely had LWS.My brother and I both have been tested genetically along with my nephew and all have tested to have LWS. Although interesting enough my brother has no orthopaedic ailments.

Posted Aug 9, 2020 by Merisa 1500

Is Léri-weill Dyschondrosteosis hereditary?

Léri-weill Dyschondrosteosis life expectancy

What is the life expectancy of someone with Léri-weill Dyschondrosteosis?

3 answers
Celebrities with Léri-weill Dyschondrosteosis

Celebrities with Léri-weill Dyschondrosteosis

1 answer
Is Léri-weill Dyschondrosteosis contagious?

Is Léri-weill Dyschondrosteosis contagious?

5 answers
Natural treatment of Léri-weill Dyschondrosteosis

Is there any natural treatment for Léri-weill Dyschondrosteosis?

1 answer
ICD9 and ICD10 codes of Léri-weill Dyschondrosteosis

ICD10 code of Léri-weill Dyschondrosteosis and ICD9 code

2 answers
Living with Léri-weill Dyschondrosteosis

Living with Léri-weill Dyschondrosteosis. How to live with Léri-weill Dysch...

3 answers
Léri-weill Dyschondrosteosis diet

Léri-weill Dyschondrosteosis diet. Is there a diet which improves the quali...

3 answers
History of Léri-weill Dyschondrosteosis

What is the history of Léri-weill Dyschondrosteosis?

1 answer

World map of Léri-weill Dyschondrosteosis

Find people with Léri-weill Dyschondrosteosis through the map. Connect with them and share experiences. Join the Léri-weill Dyschondrosteosis community.

Stories of Léri-weill Dyschondrosteosis

LÉRI-WEILL DYSCHONDROSTEOSIS STORIES
Léri-weill Dyschondrosteosis stories
My mother, my sister, my 2 daughters and myself all have Leri-Weill Dyschondrosteosis. My mother was quite tall at 5'2'......I am only about 4'9, my sister about 4'11, as are both of my daughters. My mother was the first person we KNOW for sure ha...
Léri-weill Dyschondrosteosis stories
My daughter is very small. In the hospital they find out she have Leri-Weill. Her dad is tested and have leri-Weill but only as a carrier. He is tall.
Léri-weill Dyschondrosteosis stories
My partner has Leri Weill and we recently had a baby who also has this condition. My partner has never had any treatment for any issues associated with his LWD we are now looking into support around the associated wrist pain. I’m interested in s...

Tell your story and help others

Tell my story

Léri-weill Dyschondrosteosis forum

LÉRI-WEILL DYSCHONDROSTEOSIS FORUM

Ask a question and get answers from other users.

Ask a question

Find your symptoms soulmates

From now on you can add your symptoms in diseasemaps and find your symptoms soulmates. Symptoms soulmates are people with similar symptoms to you.

Symptoms soulmates

Add your symptoms and discover your soulmates map

Soulmates map