How do I know if I have Marshall syndrome - PFAPA?

Marshall syndrome, also known as PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis) syndrome, is a rare genetic disorder that primarily affects children. It is characterized by recurrent episodes of fever, mouth ulcers, sore throat, and swollen lymph nodes in the neck.

Diagnosing Marshall syndrome - PFAPA

Diagnosing Marshall syndrome - PFAPA can be challenging as its symptoms can be similar to other conditions. However, there are certain key features that can help identify the syndrome:

• Recurrent fever: Children with Marshall syndrome - PFAPA experience regular episodes of high fever that last for about 3-6 days. The fever typically occurs at regular intervals, ranging from every 3-8 weeks.


• Mouth ulcers: Aphthous stomatitis, or mouth ulcers, are a common symptom of Marshall syndrome - PFAPA. These painful sores can appear on the inside of the cheeks, lips, or tongue.


• Pharyngitis: Sore throat is another frequent symptom. The throat may appear red and inflamed during episodes.


• Adenitis: Swollen lymph nodes in the neck, known as adenitis, are a characteristic feature of Marshall syndrome - PFAPA. These swollen glands can be tender to touch.

Seeking medical evaluation

If you suspect that you or your child may have Marshall syndrome - PFAPA, it is important to consult a healthcare professional for a proper evaluation. The doctor will review the medical history, conduct a physical examination, and may order additional tests to rule out other conditions.

Treatment and management

While there is no cure for Marshall syndrome - PFAPA, there are treatment options available to manage the symptoms and reduce the frequency and severity of episodes. This may include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs): Medications like ibuprofen or naproxen can help reduce fever and relieve pain during episodes.


• Corticosteroids: In some cases, corticosteroids may be prescribed to control symptoms during episodes.


• Tonsillectomy: Surgical removal of the tonsils has shown to be effective in some individuals with recurrent episodes.

Conclusion

If you suspect Marshall syndrome - PFAPA based on the recurrent fever, mouth ulcers, sore throat, and swollen lymph nodes, it is important to consult a healthcare professional for an accurate diagnosis. They will be able to evaluate your symptoms, rule out other conditions, and provide appropriate management strategies to improve your quality of life.