What is the prevalence of Palmoplantar Keratoderma?
How many people does Palmoplantar Keratoderma affect? Does it have the same prevalence in men and women? And in the different countries?
Palmoplantar Keratoderma (PPK) is a rare genetic disorder characterized by thickening of the skin on the palms of the hands and soles of the feet. The prevalence of PPK varies depending on the specific subtype, with estimates ranging from 1 in 2,000 to 1 in 100,000 individuals worldwide. Although PPK can affect people of all ages and ethnicities, it is more commonly observed in certain populations. Early diagnosis and management are crucial for individuals with PPK to alleviate symptoms and improve quality of life.
Palmoplantar Keratoderma (PPK) is a rare genetic disorder characterized by thickening of the skin on the palms of the hands and soles of the feet. It can present in various forms, including diffuse, focal, or punctate patterns. PPK can be inherited in an autosomal dominant, autosomal recessive, or X-linked manner.
Due to its rarity and the lack of comprehensive epidemiological studies, the exact prevalence of PPK is not well-established. However, it is estimated to affect approximately 1 in 20,000 individuals worldwide. The prevalence may vary among different populations and regions.
PPK can manifest at any age, from infancy to adulthood, and its severity can range from mild to severe. The condition often leads to discomfort, pain, and functional impairment, affecting an individual's quality of life.
While there is no cure for PPK, management focuses on symptom relief and preventing complications. This may involve regular use of emollients, keratolytic agents, and other topical treatments to soften the skin and reduce thickening. In severe cases, additional interventions such as surgical procedures or physical therapy may be considered.
