Clinical manifestations may include: uncontrollable high blood pressure, profuse sweating, facial flushing, heart palpitations, shaking, mottling on arms, hands, and legs. Testing for pheos include a 24 hour urine test and a blood plasma test for excess metanephrines. Radiologic testing is done to verify the presence of a secreting tumor and may include a CT scan, adrenal CT scan, MRI, PET scan and/ or MIBG scan. Testing and/or scans are ordered by an Endocrinologist.