Celebrities with Progressive Multifocal Leukoencephalopathy (PML)

Progressive Multifocal Leukoencephalopathy (PML) is a rare and potentially life-threatening viral infection that affects the central nervous system. It is caused by the JC virus, which is commonly found in the general population but usually remains dormant in healthy individuals. However, in people with weakened immune systems, such as those with HIV/AIDS or undergoing immunosuppressive therapy, the JC virus can reactivate and lead to the development of PML.

PML has been known to affect individuals from all walks of life, including celebrities. While it is important to respect their privacy and focus on their journey rather than sensationalizing their condition, it is worth acknowledging some well-known figures who have publicly shared their experiences with PML.

1. Richard Pryor

Richard Pryor, the legendary American stand-up comedian and actor, was diagnosed with PML in 1986. Pryor had been living with multiple sclerosis (MS) for several years, which likely contributed to his weakened immune system. He openly discussed his battle with PML and MS, shedding light on the challenges faced by individuals living with these conditions.

2. Jacob Lusk

Jacob Lusk, a finalist on the tenth season of American Idol, revealed in 2012 that he had been diagnosed with PML. Lusk had been living with HIV since childhood and was undergoing treatment for the virus when he developed PML. Despite the difficulties he faced, Lusk remained positive and continued to pursue his passion for music.

3. Timmy Matley

Timmy Matley, the lead vocalist of the British-Irish band The Overtones, passed away in 2018 after battling PML. Matley had been diagnosed with skin cancer in 2016 and subsequently developed PML as a complication of his treatment. His untimely death was a tragic loss for the music industry.

4. Natascha McElhone

Natascha McElhone, a British actress known for her roles in films like "The Truman Show" and TV series like "Californication," experienced the devastating impact of PML firsthand. In 2008, McElhone's husband, plastic surgeon Dr. Martin Hirigoyen Kelly, passed away due to complications of PML. His death prompted McElhone to become an advocate for PML awareness and research.

5. David "Stringbean" Akeman

David "Stringbean" Akeman, a renowned American country music banjo player and comedian, fell victim to PML in 1973. Akeman and his wife were tragically murdered during a robbery at their home, but the autopsy revealed that he had been suffering from PML at the time of his death. His contributions to the music industry and the tragedy surrounding his passing brought attention to the impact of PML.

These are just a few examples of celebrities who have been affected by PML. It is important to remember that PML can affect anyone with a weakened immune system, regardless of their fame or status. The experiences of these individuals highlight the challenges faced by those living with PML and the importance of raising awareness about this rare condition.