Sinonasal undifferentiated carcinoma (SNUC) is a rare and aggressive type of cancer that arises in the nasal cavity and paranasal sinuses. It accounts for approximately 3% of all sinonasal malignancies. SNUC typically affects adults, with a slight male predominance. Due to its rarity, the exact prevalence of SNUC is not well-established. However, studies suggest that it is a relatively uncommon malignancy. Early diagnosis and prompt treatment are crucial for improving outcomes in patients with SNUC.
Sinonasal undifferentiated carcinoma (SNUC) is a rare and aggressive type of cancer that arises in the nasal cavity and paranasal sinuses. Due to its rarity, the prevalence of SNUC is relatively low compared to other types of cancers.
Although exact prevalence rates are not well-established, studies suggest that SNUC accounts for approximately 0.5% to 3% of all sinonasal malignancies. It predominantly affects adults, with a peak incidence in the fifth to seventh decades of life.
SNUC is characterized by its highly invasive nature and tendency to spread to nearby structures, making it challenging to treat. The symptoms of SNUC, such as nasal obstruction, epistaxis (nosebleeds), and facial pain, often mimic those of other sinonasal conditions, leading to delayed diagnosis and treatment.
Given its rarity and aggressive behavior, SNUC requires a multidisciplinary approach involving surgery, radiation therapy, and chemotherapy. Prognosis for SNUC is generally poor, with a high risk of local recurrence and distant metastasis.