What is Systemic Capillary Leak Syndrome

Systemic Capillary Leak Syndrome (SCLS) is a rare and potentially life-threatening condition characterized by recurrent episodes of severe fluid leakage from the small blood vessels into surrounding tissues. This excessive leakage leads to a sudden drop in blood volume, resulting in low blood pressure, hemoconcentration, and organ dysfunction.

The exact cause of SCLS is still unknown, but it is believed to be related to abnormalities in the endothelial cells lining the blood vessels. These abnormalities cause the endothelial cells to become more permeable, allowing fluid and proteins to leak out of the blood vessels.

Individuals with SCLS typically experience episodes of severe symptoms, including rapid onset of swelling, low blood pressure, hemoconcentration, and organ failure. These episodes can last for a few days to a week and may require intensive medical intervention.

Currently, there is no cure for SCLS, and treatment focuses on managing the symptoms and preventing complications. This may involve intravenous fluids, medications to stabilize blood pressure, and close monitoring of organ function.

Due to the rarity of SCLS, it is crucial for individuals with this condition to receive specialized medical care from healthcare professionals familiar with the syndrome.