What is Tooth and Nail Syndrome

Tooth and Nail Syndrome is a rare genetic disorder that affects the development of teeth and nails. It is also known as Witkop syndrome or hypodontia with nail dysplasia. Individuals with this syndrome typically have missing or underdeveloped teeth, which can lead to dental problems and difficulties with chewing and speaking.

The condition also affects the nails, causing them to be abnormally shaped, brittle, or absent. This can impact the individual's ability to perform fine motor tasks and may cause discomfort or pain.

Tooth and Nail Syndrome is usually inherited in an autosomal dominant manner, meaning that a person only needs to inherit the gene mutation from one parent to develop the syndrome. However, in some cases, it can occur sporadically without a family history.

Treatment for Tooth and Nail Syndrome focuses on managing the dental and nail abnormalities. This may involve dental interventions such as orthodontics, dental implants, or dentures to improve oral function and appearance. Nail care and protection strategies can also be implemented to minimize discomfort and prevent further damage.