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What is the prevalence of Uterine Leiomyosarcoma?

How many people does Uterine Leiomyosarcoma affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Uterine Leiomyosarcoma

Uterine leiomyosarcoma is a rare type of cancer that develops in the smooth muscle cells of the uterus. It accounts for approximately 1-2% of all uterine malignancies. Although it is considered a rare cancer, it is the most common type of uterine sarcoma. Uterine leiomyosarcoma primarily affects women in their 40s and 50s, with a slightly higher prevalence in African American women. Due to its rarity, more research is needed to better understand the risk factors and develop effective treatment strategies.



Uterine leiomyosarcoma is a rare and aggressive form of cancer that arises from the smooth muscle cells of the uterus. It accounts for approximately 1-2% of all uterine malignancies. Although it is considered a rare cancer, its prevalence varies depending on several factors such as age, race, and genetic predisposition.


Age: Uterine leiomyosarcoma primarily affects women in their 40s and 50s, with the average age of diagnosis being around 55 years.


Race: Studies have shown that uterine leiomyosarcoma is more common in African American women compared to women of other races.


Genetic Predisposition: Certain genetic conditions, such as hereditary leiomyomatosis and renal cell cancer syndrome, have been associated with an increased risk of developing uterine leiomyosarcoma.


Due to its rarity, there is limited data on the exact prevalence of uterine leiomyosarcoma. However, it is estimated that the annual incidence rate is approximately 0.64 cases per 100,000 women. It is important to note that early detection and prompt treatment are crucial for improving outcomes in patients with uterine leiomyosarcoma.


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Prevalence of Uterine Leiomyosarcoma

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World map of Uterine Leiomyosarcoma

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