What is the prevalence of Wolf Hirschhorn Syndrome?
How many people does Wolf Hirschhorn Syndrome affect? Does it have the same prevalence in men and women? And in the different countries?
Wolf-Hirschhorn Syndrome is a rare genetic disorder caused by a deletion on chromosome 4. It is estimated to affect approximately 1 in 50,000 to 1 in 100,000 live births worldwide. The syndrome is characterized by distinct facial features, intellectual disability, delayed growth, and various medical complications. Although the prevalence is relatively low, it is important to provide support and resources for individuals and families affected by this condition.
Wolf-Hirschhorn Syndrome (WHS) is a rare genetic disorder caused by a deletion on the short arm of chromosome 4. It was first described by Drs. U. Wolf, K. Hirschhorn, and C. J. Porter in the late 1960s. The prevalence of WHS is estimated to be around 1 in 50,000 to 1 in 100,000 live births, making it a relatively uncommon condition.
WHS is characterized by distinct facial features, intellectual disability, delayed growth and development, seizures, and various physical abnormalities. The severity of symptoms can vary widely among individuals, even among those with the same chromosomal deletion.
Due to its rarity, WHS often goes undiagnosed or misdiagnosed, leading to challenges in understanding its true prevalence. However, advancements in genetic testing techniques have improved diagnostic accuracy in recent years.
While there is no cure for WHS, treatment focuses on managing the symptoms and providing supportive care. Early intervention programs, specialized therapies, and regular medical monitoring can help improve the quality of life for individuals with WHS and their families.
