What is the prevalence of Wolfram Syndrome?
How many people does Wolfram Syndrome affect? Does it have the same prevalence in men and women? And in the different countries?
Wolfram Syndrome is a rare genetic disorder characterized by a combination of diabetes mellitus, optic atrophy, deafness, and neurological abnormalities. It is estimated to affect approximately 1 in 770,000 individuals worldwide. The syndrome is inherited in an autosomal recessive pattern, meaning both parents must carry a copy of the mutated gene for their child to be affected. While the prevalence of Wolfram Syndrome is low, it is important to raise awareness and provide support for individuals and families affected by this condition.
Wolfram Syndrome is a rare genetic disorder that affects multiple systems in the body. It is estimated to occur in approximately 1 in 770,000 individuals worldwide, making it an extremely rare condition.
The syndrome is characterized by a combination of symptoms including diabetes mellitus, optic atrophy (progressive vision loss), diabetes insipidus (excessive thirst and urination), and deafness. Other features may include neurological abnormalities, psychiatric disorders, and urinary tract problems.
Due to its rarity, Wolfram Syndrome often goes undiagnosed or misdiagnosed, leading to delayed treatment and management. The condition is typically inherited in an autosomal recessive manner, meaning both parents must carry a copy of the mutated gene for their child to be affected.
While there is currently no cure for Wolfram Syndrome, early diagnosis and appropriate management can help alleviate symptoms and improve quality of life. Genetic counseling and support services are crucial for affected individuals and their families.
