I feel that it's up to the individual person. Adrenal Insufficiency is on a spectrum. Each person has their own unique issues with it. Some it can be completely disabling and others can live a fully functional life with stable treatment. Secondary and other health concerns also greatly play into this along with factors such as dead or atrophied adrenal glands, panhypopituitarism, diabetes, etc. Also, some careers may be considered strenuous to one person and not another. I would suggest avoiding careers that can be extremely dangerous with high risk of injury or physical exhaustion.