Down Syndrome synonyms

Down Syndrome, also known as Trisomy 21, is a genetic disorder that occurs when an individual has a full or partial extra copy of chromosome 21. This additional genetic material alters the course of development and causes various physical and intellectual disabilities.

People with Down Syndrome typically exhibit certain physical characteristics, such as slanted eyes, a flat facial profile, a small nose, and a short neck. They may also have low muscle tone, which can affect their motor skills and coordination. Additionally, individuals with Down Syndrome often experience cognitive delays and intellectual disabilities of varying degrees.

While Down Syndrome is a well-known term, it is important to note that it is not a disease or an illness. It is a naturally occurring condition that affects individuals from all ethnicities and socioeconomic backgrounds.

There are several synonyms or alternative names used to refer to Down Syndrome. These include:

• Trisomy 21: This term refers to the presence of an extra copy of chromosome 21 in every cell of the body.


• Mongolism: This outdated term was historically used due to the physical similarities some individuals with Down Syndrome have to people of Mongolian descent. However, it is now considered derogatory and inappropriate.


• Down's: This abbreviation is commonly used in informal contexts to refer to Down Syndrome.


• Down's Syndrome: This is another variation of the term Down Syndrome.


• Trisomy G: This term is sometimes used to refer to Trisomy 21, with the "G" representing the 21st letter of the alphabet.

It is important to use respectful and inclusive language when discussing Down Syndrome, focusing on the individual rather than their condition. People with Down Syndrome lead fulfilling lives and contribute to their communities in various ways.