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What is the prevalence of Goodpasture syndrome?

How many people does Goodpasture syndrome affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Goodpasture syndrome

Goodpasture syndrome is a rare autoimmune disorder characterized by the presence of autoantibodies that attack the kidneys and lungs. It affects approximately 1 in every 1 million people, making it a highly uncommon condition. The syndrome primarily affects young adults, with males being slightly more susceptible than females. Symptoms may include coughing up blood, difficulty breathing, fatigue, and kidney-related issues. Early diagnosis and treatment are crucial to prevent severe organ damage. While Goodpasture syndrome is rare, it is important to be aware of its symptoms and seek medical attention if necessary.



Goodpasture syndrome is a rare autoimmune disorder characterized by the presence of autoantibodies that attack the kidneys and lungs. It was first described by Ernest Goodpasture in 1919. The syndrome primarily affects young adults, with a peak incidence between the ages of 20 and 30.



The prevalence of Goodpasture syndrome is relatively low, estimated to be around 1 in 1 million individuals. Although it is considered rare, it is important to note that prevalence rates may vary across different populations and regions.



Goodpasture syndrome can have severe consequences if left untreated. The autoantibodies target the basement membrane of the kidneys and lungs, leading to glomerulonephritis and pulmonary hemorrhage. Prompt diagnosis and treatment are crucial to prevent irreversible damage to these organs.



Treatment typically involves a combination of immunosuppressive medications and plasma exchange therapy to remove the harmful autoantibodies. With early intervention, the prognosis for Goodpasture syndrome has improved over the years, but it remains a serious condition requiring ongoing medical management.


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3 answers
There is no indication of who is most affected by the disease that I know of, however it is believed 1 in every 2 million worldwide will be diagnosed

Posted Jul 6, 2017 by Paul 2200
Mostly affects men than women and it is 1-1,000,000,000. From 18-30's or late 50's on.

Posted Oct 9, 2017 by Debbie 2000

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My names Angela D I've had goodpastures for 10 years, I was 14 almost 15 when my lungs began to bleed, I at first was diagnosed with phamonia and was treated with that but I never got better I actually got worse, I was sent to Minneapolis children's ...
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In 2007, I began to have trouble breathing and I started coughing up blood. This went on for several months and I was d diagnosed with pneumonia. I spent nine days in the hospital on IV antibiotics. I got better and didn't have any other symptoms unt...
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I been sick on n off with stomache bugs etc since having my daughter in 2012.. last year 2015)- i was sick for weeks on end in n out of dr clinics having bloods done n spending most days in bed allday. I noticed over a period of about 3months my body...
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March 2016, things were looking pretty bleak. I'd started a new job in the January but, due to a lack of adequate support or training, it was decided I "wasn't suitable" and my contract was terminated. To make things worse, I'd just got a cold. So I...
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My daughter was 33 with 3 small children when she was diagnosised with GPS.  She spent months in the hospital and has been in and out more times than I can count the past 5 years.   I think the hardest thing about being a parent of a GPS patient is...

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