What is the prevalence of Graft Versus Host Disease?
How many people does Graft Versus Host Disease affect? Does it have the same prevalence in men and women? And in the different countries?
Graft Versus Host Disease (GVHD) is a common complication that can occur after a stem cell or bone marrow transplant. The prevalence of GVHD varies depending on several factors, including the type of transplant and the donor source. In allogeneic transplants, where the donor is not a perfect match, the prevalence of acute GVHD is around 30-60%, while chronic GVHD affects approximately 40-70% of patients. However, with improved understanding and advancements in transplant techniques, the incidence and severity of GVHD have been reduced in recent years.
Graft Versus Host Disease (GVHD) is a common complication that can occur after a stem cell or bone marrow transplant. It arises when the transplanted cells recognize the recipient's body as foreign and attack the recipient's tissues. The prevalence of GVHD varies depending on several factors, including the type of transplant, the source of the donor cells, and the recipient's health condition.
In allogeneic transplants, where the donor is a close genetic match to the recipient, the prevalence of acute GVHD is approximately 30-60%. This means that a significant proportion of patients may experience symptoms within the first few months after the transplant. Chronic GVHD, which occurs later and can last for years, has a prevalence of around 30-50%.
However, prevention and treatment strategies have improved over the years, leading to better outcomes and reduced severity of GVHD. Close monitoring, immunosuppressive medications, and advances in transplant techniques have contributed to lowering the impact of GVHD on patients' quality of life.
