Which are the causes of Hyperhidrosis?

Hyperhidrosis is a medical condition characterized by excessive sweating beyond what is necessary to regulate body temperature. It can significantly impact an individual's quality of life, causing embarrassment, discomfort, and social anxiety. While the exact cause of hyperhidrosis is not fully understood, there are several factors that are believed to contribute to its development.

1. Primary Hyperhidrosis

Primary hyperhidrosis is the most common form of the condition and typically starts during adolescence or early adulthood. It is thought to be caused by an overactivity of the sweat glands, which are controlled by the sympathetic nervous system. The exact reason behind this overactivity is unknown, but it is believed to have a genetic component as it often runs in families.

2. Secondary Hyperhidrosis

Secondary hyperhidrosis is less common and is usually a result of an underlying medical condition or medication. It can occur at any age and often affects larger areas of the body compared to primary hyperhidrosis. Some of the known causes of secondary hyperhidrosis include:

a. Medical Conditions

Various medical conditions can trigger secondary hyperhidrosis. These may include:

• Endocrine disorders: Conditions such as hyperthyroidism, diabetes, and menopause can disrupt the body's hormonal balance, leading to excessive sweating.


• Neurological disorders: Certain neurological conditions like Parkinson's disease, stroke, and autonomic neuropathy can affect the functioning of the sweat glands.


• Infections: Certain infections, such as tuberculosis or HIV, can cause hyperhidrosis as a secondary symptom.


• Cancer: Some types of cancer, particularly lymphoma and leukemia, can cause excessive sweating as a result of the body's immune response.


• Cardiovascular disorders: Heart disease, heart attack, and high blood pressure can contribute to secondary hyperhidrosis.

b. Medications

Certain medications can also induce hyperhidrosis as a side effect. These may include:

• Antidepressants: Selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants are known to cause excessive sweating in some individuals.


• Antipyretics: Medications used to reduce fever, such as aspirin and acetaminophen, can lead to increased sweating.


• Hormonal drugs: Hormone-based medications like hormone replacement therapy (HRT) or oral contraceptives may trigger hyperhidrosis in some individuals.


• Some antibiotics: Certain antibiotics, such as linezolid and fluoroquinolones, have been associated with excessive sweating.

3. Emotional Triggers

Emotional factors can exacerbate hyperhidrosis symptoms, particularly in individuals with primary hyperhidrosis. Stress, anxiety, nervousness, and excitement can all stimulate the sympathetic nervous system, leading to increased sweating. This is commonly referred to as emotional sweating.

4. Lifestyle Factors

While not direct causes of hyperhidrosis, certain lifestyle factors can contribute to its severity. These include:

• Caffeine and alcohol: Consumption of caffeinated beverages and alcohol can stimulate the sweat glands, leading to increased sweating.


• Spicy foods: Spicy foods can trigger sweating in some individuals, although the effect is temporary.


• Tight clothing: Wearing tight or synthetic clothing can trap heat and moisture, exacerbating sweating.


• Heat and humidity: Hot and humid environments can make hyperhidrosis symptoms more pronounced.

It is important to note that hyperhidrosis is a medical condition that should be diagnosed and treated by a healthcare professional. If you suspect you have hyperhidrosis, it is recommended to seek medical advice to determine the underlying cause and explore appropriate treatment options.