What is Klippel-Trénaunay-Weber Syndrome

Klippel-Trénaunay-Weber Syndrome (KTWS) is a rare congenital disorder characterized by a triad of symptoms: port-wine stain birthmark, varicose veins, and abnormal growth of bones and soft tissues. This condition primarily affects the limbs, but can also involve other body parts.

The port-wine stain birthmark is a dark red or purple discoloration of the skin caused by enlarged blood vessels. It is typically present at birth and can vary in size and location. Varicose veins are swollen, twisted veins that may cause discomfort and affect blood circulation. The abnormal growth of bones and soft tissues can lead to limb overgrowth or asymmetry.

The exact cause of KTWS is unknown, but it is believed to result from abnormal development of blood vessels during fetal development. While the condition is present at birth, symptoms may become more noticeable over time. Treatment options focus on managing symptoms and may include compression stockings, physical therapy, medications to alleviate pain, and in some cases, surgery.

It is important for individuals with KTWS to receive appropriate medical care and support to address the physical and emotional challenges associated with this condition.