What is the prevalence of Nance-Horan Syndrome?
How many people does Nance-Horan Syndrome affect? Does it have the same prevalence in men and women? And in the different countries?
Nance-Horan Syndrome is a rare genetic disorder characterized by various ocular and dental abnormalities. It primarily affects males, with an estimated prevalence of approximately 1 in 30,000 to 40,000 individuals. The syndrome is inherited in an X-linked pattern, meaning it is passed down from mothers to their sons. Symptoms may include cataracts, facial features changes, dental anomalies, and intellectual disability in some cases. Early diagnosis and management are crucial for individuals with Nance-Horan Syndrome to ensure appropriate treatment and support.
Nance-Horan Syndrome is a rare genetic disorder that primarily affects the development of the eyes and teeth. Due to its rarity, the prevalence of this syndrome is relatively low. Exact figures regarding its occurrence are not readily available, but it is estimated to affect approximately 1 in 40,000 to 100,000 individuals worldwide.
This syndrome is inherited in an X-linked dominant manner, meaning it predominantly affects males and can be passed on by affected females to their children. The severity of Nance-Horan Syndrome can vary widely among individuals, even within the same family.
Characteristics of this syndrome include various eye abnormalities such as cataracts, microphthalmia (small eyes), strabismus (crossed eyes), and other vision impairments. Dental anomalies like missing or misshapen teeth are also common. Additionally, individuals with Nance-Horan Syndrome may exhibit distinct facial features and intellectual disabilities in some cases.
Diagnosis of Nance-Horan Syndrome is typically based on clinical evaluation, family history, and genetic testing. Although there is no cure for this syndrome, management focuses on addressing specific symptoms and providing appropriate support and care.
