My daughter (now 16) has nephrogenic diabetes insipdus since birth. She was diagnosed when she was 4 months old. Until her 7th birthday she got Esidrix and Indometacin. After her 7th birthday she could stop taking the medicine because her body was able to compensate her disease by drinking. Now she drinks 10-12 litres of water a day.
The reason for her illness was not found. Mother no NDI, father no NDI. The gene analysis said spontaneous gene mutation.