What is the prevalence of Protein C Deficiency?

Protein C Deficiency is a relatively rare genetic disorder that affects the body's ability to produce a protein called Protein C, which plays a crucial role in regulating blood clotting. The prevalence of this condition varies among different populations and regions. In the general population, Protein C Deficiency is estimated to affect approximately 1 in 4,000 individuals. However, the prevalence can be higher in certain ethnic groups, such as those of European descent, where it may affect 1 in 200 to 500 individuals.

Protein C Deficiency can be inherited in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the defective gene from either parent to develop the condition. However, it is important to note that not all individuals with Protein C Deficiency will experience symptoms or complications. The severity of the disorder can also vary, ranging from mild to severe cases.

Early diagnosis and appropriate management are crucial for individuals with Protein C Deficiency to prevent complications such as deep vein thrombosis, pulmonary embolism, or other clotting disorders. If you suspect you or a family member may have Protein C Deficiency, it is important to consult with a healthcare professional for proper evaluation and guidance.