What is Prune Belly Syndrome

Prune Belly Syndrome, also known as Eagle-Barrett syndrome, is a rare congenital disorder that primarily affects males. It is characterized by a triad of symptoms: absence or severe underdevelopment of the abdominal muscles, undescended testicles (cryptorchidism), and urinary tract abnormalities.

The absence or weakness of abdominal muscles gives the abdomen a wrinkled or "prune-like" appearance, hence the name. This can lead to various complications such as poor digestion, respiratory issues, and difficulty with physical activities.

Undescended testicles occur when one or both testicles fail to move from the abdomen into the scrotum. This can affect fertility and increase the risk of testicular cancer.

Urinary tract abnormalities are common in individuals with Prune Belly Syndrome. These can include abnormalities in the kidneys, ureters, and bladder, leading to urinary tract infections, kidney damage, and other complications.

The exact cause of Prune Belly Syndrome is unknown, but it is believed to result from a combination of genetic and environmental factors. Diagnosis is typically made through physical examination, imaging tests, and genetic testing.

Treatment for Prune Belly Syndrome focuses on managing the associated complications. This may involve surgical interventions to correct urinary tract abnormalities, hormone therapy for undescended testicles, and supportive care for abdominal muscle weakness. Early intervention and a multidisciplinary approach involving urologists, surgeons, and other specialists can help improve outcomes for individuals with Prune Belly Syndrome.